Curriculum Vitae and Publications:

Ekaterina S. Timofeeva MD, PhD

5025 E Pacific Coast HWY, apt P318, Long Beach, CA 90804
Cell: 562-336-8371
ekaterina.s.timofeeva@gmail.com

Summary

A highly-motivated, enthusiastic, creative international medical graduate educated in medical oncology with MD and PhD degrees in medical science (oncology) with more than three years successful experience in six cancer clinical trials and one cancer research study demonstrated by 1 grant, 2 patents of inventions, 4+ publications, 3 reports and presentations at oncology conferences and with great experience in an effective management of a medical corporation with more than 25 employees seeking a Clinical Research Associate position in a field of clinical trials where my skills and experience would be useful for achieving goals of my employer.

Skills

• Self starter and driven, creative, motivated to take the initiative, and possess an ambitious curiosity.
• Responsible. Result oriented.
• Experienced at successfully managing multiple tasks with excellent accuracy and attentiveness to details.
• A great team-worker, but also great at prioritizing and managing multiple projects independently.
• Excellent communication, interpersonal, and problem-solving skills.
• Can effectively search, collect, analyze and summarize information.
• Highly experienced in medical writing and medical terminology.
• Accurate document processing and maintaining confidential information.
• Strong computer skills: MS Office (Word, Excel, Power Point, Paint, One Drive, Email), Apache Open Office, Internet search, Social Networks.
• Fluent in Russian.

Professional Experience

CEO, OOO “LICHNY DOCTOR”, Saint-Petersburg, Russia, 11/01/2011 – 08/14/2017.

• Successfully organized and managed the work of a team of more than 25 people in a medical corporation which included two medical offices. Since 2011, an amount of employees increased from 5 to 30 people, a second medical office was opened.
• More than 27000 customers have gotten medical services since 2011 - 2017.
• Created, developed medical documentation, paper and/or electronic medical forms which helped employees to perform their duties more quickly and qualitatively.
• Wrote more than 50 medical articles for patients on the website.

Medical Oncologist, OOO “LICHNY DOCTOR”, Saint-Petersburg, Russia, 11/01/2011 – 08/14/2017.

• Performed examinations and ambulatory treatments more than 1000 patients with benign breast diseases since 2011.
• Diagnosed and examined more than 100 patients with malignant breast diseases since 2011.
• Regularly observed and examined more than 50 patients who had gotten different treatments for breast cancer.
• Performed an ultrasound diagnostic of breast diseases more than 1000 patients.
• Consulted more than 100 pregnant woman and woman after delivery about breast feeding, possible problems during breast feeding. Discussed with them the ways and methods to resolve lactation problems.

Medical Oncologist, Research Institute of Oncology named after N.N. Petrov, Saint-Petersburg, Russia, 09/01/2008-10/31/2011.

• Took an active role on a team that identified, developed and performed own clinical research study concerning the treatment of patients with lung metastases using the method of isolated chemoperfusion of the lung. One grant, 2 patents of inventions, 4+ publications, 3 reports at oncology conferences are demonstrated science achievements.
• Lung cancer management and surgery, lung metastases management and surgery, skin melanoma management and surgery, thyreoid cancer management and surgery.

Clinical Research Sub-Investigator, Research Institute of Oncology named after N.N. Petrov, Saint-Petersburg, Russia, 09/01/2008-10/31/2011.

• Participated in six cancer clinical trials as a Clinical Research Sub-Investigator performed all procedures of trials according with GCP and FDA requires and successfully performed duties of clinical research coordinator of these trials:

1. Study of GSK2302025A Antigen-Specific Cancer Immunotherapeutic in Patients With Metastatic Melanoma (DERMA).
2. Study of GSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Resectable MAGE-A3 Positive Non-Small Cell Lung Cancer (MAGRIT).
3. Study of GSK2302025A Antigen-Specific Cancer Immunotherapeutic in Patients With Metastatic Melanoma (PRAME).
4. Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic as First-line Treatment of Patients With Unresectable Metastatic Melanoma (PREDICT).
5. A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Single-agent Tarceva® (Erlotinib) Following Complete Tumor Resection With or Without Adjuvant Chemotherapy in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma Who Have EGFR-positive Tumorspr.
6. Efficacy and safety of XM22 in patients with non small cell lung cancer receiving cisplatin / etoposide chemotherapy. A multinational, multicentre, randomised, double-blind placebo-controlled study.

• Screened, recruited patients to studies.
• Obtained informed consent from potential study subjects.
• Confirmed eligibility of study subjects.
• Performed clinical examinations.
• Evaluated laboratory and other medical reports.
• Supervised administration of study drug.
• Observed, measured and recorded effects of drug
• Evaluated, managed and reported all adverse events.
• Kept and made study documentation available for data verification purposes.
• Maintained research practices using Good Clinical Practice (GCP) guidelines.
• Participated in monitoring and auditing activities.
• Maintained strict patient confidentiality according to HIPAA regulations and applicable law.

Clinical Research Coordinator, Research Institute of Oncology named after N.N. Petrov, Saint-Petersburg, Russia, 09/01/2008-10/31/2011.

• Scheduled patients for research visits and research procedures.
• Scheduled and participated in monitoring and auditing activities.
• Documented thoroughly on Case Report Forms (CRFs) the following; changes in patient condition, adverse events, concomitant medication use, protocol compliance, response to study drug.
• Accurately entered clinical research data into Electronic Data Systems (EDCs) that were provided by the sponsors, compiled and submitted data on appropriate forms according to trial requirements.
• Answered queries to complete resolution during and after monitoring visits. Responded to queries timely.
• Prepared and shipped the samples.
• Throughly ordered, stored & maintained an inventory of studies supplies.
• Participated in preparation of a site and monitor trial documentation.
• Collaborated, communicated and successfully solved current problems with patients, research team members, Principal Investigator (PI) and study monitors at all stages of the clinical trials.

Pharmacy medical representative, part-time, “ABBOTT-Russia”, Saint-Petersburg, Russia, 08/2007 – 05/2011.

• Acquainted pharmacists with RX and OTC company's medications. Gave lectures and seminars for pharmacists about RX and OTC company's medications with the aim of increasing marketability. Achieved sales growth up to 20% in some OTC company's medications.
• Worked at the company's stand during the conferences. Introduced RX and OTC company's medications to the visitors.

Education

PhD in Medical Sciences / Oncology, Research Institute of Oncology named after N.N. Petrov, Saint-Petersburg, Russia, 2011.
Medical Oncology Residency Program, Saint-Petersburg State Medical Academy named after I.I. Mechnikov, Research Institute of Oncology named after N.N. Petrov, Saint-Petersburg, Russia, 2006 - 2008.
Medical Doctor, Saint-Petersburg State Medical Academy named after I.I. Mechnikov, Saint-Petersburg, Russia, 2000 - 2006.

Certifications and Courses

Certified in Oncology, September 2008 by Saint-Petersburg State Medical Academy named after I.I. Mechnikov, Saint-Petersburg, Russia.
Certified in Oncology, September 2013 by Saint-Petersburg State Pediatric Academy, Saint-Petersburg, Russia.
Certified in Ultrasound Diagnostic, December 2016 by North-West Medical University, Saint-Petersburg, Russia.

Grants

• Received Grant for development of the technique of isolated lung perfusion with lung metastases from Foundation for Assistance to Small Innovative Enterprises in Science and Technology, Saint-Petersburg, Russia, 2010 - 2012.

Patents of Inventions

1. Levchenko EV, Senchik KY, Barchuk AS, Lemekhov VG, Gelfond VM, Timofeeva ES, inventors; Federal State Institution "Scientific Research Institute of Oncology named after NN Petrov Federal Agency for High-Tech Medical Care" assignee. Sposob izolirovannoj himioperfuzii legkogo pri ego metastaticheskom porazhenii [Method of isolated chemoperfusion of a lung with its metastatic lesion]. Russian Federation Patent RU 2406453. 2010 Dec 20. Russian. http://www.freepatent.ru/patents/2406453
2. Levchenko EV, Senchik KY, Vagner RI, Gelfond VM, Arsen'ev AI, Timofeeva ES, inventors; Federal State Institution "Scientific Research Institute of Oncology named after NN Petrov Federal Agency for High-Tech Medical Care" assignee. Sposob selektivnoj izolirovannoj legochnoj perfuzii citostatikov verhnej doli levogo ili verhnej i srednej doli pravogo legkogo pri ih metastaticheskom porazhenii i ustrojstvo dlya ego osushchestvleniya. [Method of selective isolated pulmonary perfusion of cytostatic agents in an upper lobe of a left lung or an upper and medium lobe of a right lung with its metastatic lesion and device for its realization]. Russian Federation Patent RU 2432123, 2011 Oct 27. Russian. http://www.freepatent.ru/patents/2432123

Reports and Presentations

1. Isolated lung chemoperfusion with the citostatic agents for metastases of malignant tumors. Report and presentation at The XV Russian Oncological Congress, Moscow, November 17, 2011. https://rosoncoweb.ru/events/2011/11/15/video/valday/17/12/
2. Isolated lung chemoperfusion with the citostatic agents for metastases of malignant tumors. Poster report at The XV Russian Oncological Congress, Moscow, November 15-17, 2011.
3. Method of regional chemoperfusion of lungs. Indications. The first results. Report and presentation at The Scientific-Practical Conference “Multidisciplinary approaches in oncology”, Moscow, April 5, 2012.

List of Publications

1. Sidorova AA, Grigoriev AV, Timofeeva ES, Levchenko EV. Determination of Dihydroxymelphalan in Perfusate, Blood Plasma, and Lung Tissue by HPLC-MS: Use in a Pharmacokinetic Study. Journal of Analytical Chemistry, 2014;69(4):377-383. English, Russian. https://www.researchgate.net/publication/263068186_Determination_of_Dihydroxymelphalan_in_Perfusate_Blood_Plasma_and_Lung_Tissue_by_HPLC-MS_Use_in_a_Pharmacokinetic_Study

2. Levchenko EV, Senchik KY, Barchuk AS, Lemekhov VG, Timofeeva ES, Dunaevskiy IV, Gelfond VM, Gorokhov LV, Arsenev AI, Radzhabova ZA, Ergnyan SM, Dolgopolskiy MN, Moiseenko VM. [Isolated lung chemoperfusion for metastases of solid tumors]. Onkokhirurgiya [Oncosurgery], 2012;4(3):46-53. Russian. https://elibrary.ru/item.asp?id=18925064

3. Barchuk AS, Levchenko EV, Arsen'ev AI, Vagner RI, Gel'fond ML, Barchuk AA, Lemekhov VG, Kanaev SV, Ergnian SM, Gagua KE, Timofeeva ES, Beinusov DS, Tarkov SA, Mamontov OU, Levchenko NE. [Current problems in the combined therapy of lung cancer]. Vopr Onkol, 2012;58(2):253-259. Russian. https://www.ncbi.nlm.nih.gov/pubmed/22774534

4. Timofeeva ES, Levchenko EV, Moiseenko VM [Isolated perfusion of cytostatics into the lung]. Vopr Onkol, 2011;57(2):147-154. Russian. https://www.ncbi.nlm.nih.gov/pubmed/21809658

5. Timofeeva ES. Izolirovannaya himioperfuziya legkogo v kombinirovannom lechenii metastaticheskogo porazheniya legkih [Isolated pulmonary chemoperfusion in combination treatment of pulmonary metastatic lesion] [Doctoral dissertation thesis]. Saint-Petersburg (Russia): Research Institute of Oncology named after N.N. Petrov; 2011. 23 p. Russian. Retrieved from https://dlib.rsl.ru/viewer/01005004200#?page=1

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• Curriculum Vitae and Publications